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Jacqueline Seymour, Health Coach

Jacqueline Seymour

Health Coach

Reviewed By

 Dr. Frank Lipman sits on a chair, cross-legged, arm resting on the back of the chair, lightly touching his other hand that is resting on his thigh. He is wearing blue denim, a blue dress shirt and a navy textured blazer and black glasses. He is smiling, showing his front teeth looking off to the side.

Dr. Frank Lipman

Chief Medical Officer at THE WELL

Updated: 08/15/2024

Have you ever come across the term 'oxidative stress' in discussions about health and aging? If you've found yourself grappling to understand its implications for longevity, you're not alone. But fear not, we're here to shed light on this elusive concept. What exactly is oxidative stress, and why does it raise concerns for our longevity? Let’s explore its impact on aging.

What is Oxidative Stress?

Oxidative stress, which Dr. Lipman often refers to as the body “rusting,” occurs when there's an imbalance between the production of “bad” free radicals in the body and the body's ability to neutralize them with “good” antioxidants. Free radicals are unstable molecules that contain unpaired electrons, making them highly reactive. They can damage cells, proteins, and DNA by "stealing" electrons from other molecules, a process known as oxidation.

The body produces free radicals naturally through various metabolic processes, such as energy production and immune responses. However, environmental factors like pollution, radiation, smoking, and unhealthy diets can increase the production of free radicals, leading to heightened oxidative stress.

What are the causes?

Several factors can lead to oxidative stress, including:

  1. Environmental toxins - Exposure to pollutants, pesticides, heavy metals, and radiation can increase free radical production.
  2. Poor lifestyle - Smoking, excessive alcohol consumption, and a poor diet can contribute to oxidative stress.
  3. Too much stress - High levels of stress can stimulate the production of stress hormones that, in turn, increase oxidative stress. Even too much exercise can be perceived as stress! 
  4. Aging itself - As we age, our body's natural antioxidant defenses decline, making us more susceptible to oxidative stress.

What happens if we have too much oxidative stress?

Oxidative stress has a wide-ranging impact on the body and is associated with several health issues, including:

  1. Cellular damage - Free radicals can damage cell membranes, proteins, and DNA, leading to cellular dysfunction.
  2. Chronic diseases - Oxidative stress is linked to various chronic diseases, such as cardiovascular disease, diabetes, Alzheimer's disease, Parkinson's disease, and cancer.
  3. Premature aging - Oxidative stress can accelerate aging by causing skin damage, wrinkles, and reduced elasticity.
  4. Inflammation - Oxidative stress can trigger inflammation, which is a contributing factor in many chronic conditions.

How to combat oxidative stress?

Although it's impossible to eliminate oxidative stress entirely, here are several strategies you can use to minimize its impact and protect your health:

  1. Consume antioxidant-rich foods - Antioxidants can neutralize free radicals and help reduce oxidative stress. Include foods high in antioxidants, such as berries, citrus fruits, dark leafy greens, and nuts.
  2. Exercise often and consistently - Regular physical activity can boost antioxidant defenses and reduce oxidative stress. Aim for a mix of aerobic and strength-training exercises.
  3. Manage your stress - Chronic stress can exacerbate oxidative stress. Practice stress-management techniques like meditation, deep breathing, yoga, or mindfulness.
  4. Avoid environmental toxin exposure - Reduce exposure to pollutants, pesticides, and other harmful substances. Use natural cleaning products and wear protective gear if you have to use harmful substances.
  5. Prioritize your sleep - Quality sleep is crucial for cellular repair and reducing oxidative stress. Aim for 7-9 hours of sleep per night.
  6. Avoid alcohol and stop smoking - Both smoking and alcohol consumption increase oxidative stress. Quit smoking and drink alcohol in moderation, if at all.‍

Oxidative stress is a complex process that can lead to cellular damage, chronic diseases, and premature aging. By adopting a healthy lifestyle you can reduce the impact of oxidative stress and improve your overall health!

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